Best Pharmaceutical Laboratories Amsterdam Near Me

4worldlovers: Founded in 1906, Norgine is a leading European specialist pharmaceutical company with a strong global network of partnerships.

4worldlovers:
First Health Pharmaceuticals has a leading position in the field of advanced RNA biochemistry. We aim to further develop our portfolio of highly active patented RNA Helicase inhibiting lead compounds and bring revolutionary pharmaceuticals to the market that will offer new hope for patients suffering from some of the most challenging diseases of our time.


First Health Pharma developed the first ever generation of Translation Inhibitor compounds effective against HAART resistant HIV strains and is investigating potential strategies to be applied in a HIV Shock & Kill approach.


The translation of RNA to proteins is fundamental for cell survival and replication, thus First Health Pharmaceuticals has set its RNA Research priorities on the development of RNA Helicase inhibiting lead compounds.


DDX3 RNA helicase has remarkable oncogenic properties. It is overexpressed in the malignant types of Breast and Lung cancer. Our DDX3 inhibitors can be considered apoptosis-inducing targeted antitumor agents.

4worldlovers:
We help you identify optimal solid forms with high- and medium-throughput solid-state services, state-of-the-art analytical techniques and experimental work at different scales.


Science-led. Proven. We craft a route that reduces development risks and time to market


We have an extensive and proven track record in solid-state screening and research studies designed to help you explore the true potential of your molecule.


Our solid-state research team investigates the solid form of your drug substance to identify a stable salt and/or polymorphic form, with acceptable bioavailability and bulk properties. We design crystallization processes that consistently produce your desired form.


A committed project manager is at your side making it easier to identify untapped potential and seize available opportunities. Our reporting format enables our customers to drive stakeholder discussions and strategic decision-making. With a typical time frame of 6-8 weeks from delivery of the material, our screens are tailored to your budget and deadlines.

We are also one of a few companies worldwide that can handle highly potent and controlled substances.

We help you to gain knowledge of your compound’s crystal structure at an atomic level and characterize its intermolecular interactions. This helps us to obtain a wealth of information crucial for absolute configuration (enantiomers), phase identification, quality control, process development and patent protection.

Our crystallography services include X-ray diffraction, which is widely recognized as the most reliable tool for the analysis of pharmaceutical solids and crystal form identification.

Navigating complexity with the scientific expertise of our people, we can solve the crystal structure from X-ray powder diffraction where it’s not possible to obtain a crystal of the drug substance at a suitable size for data collection. We also offer X-ray powder diffraction measurements at ambient conditions and/or at variable temperatures or humidity.

Solid form screening, including salt, polymorph, co-crystal and amorphous solid dispersions, is vital for successful pharmaceutical development.

With an increase in molecule size and complexity, companies face a larger number of compounds that are either poorly soluble, difficult to crystallize or problematic with respect to desired physical-chemical properties.

Our solid-state research team has expertise in identifying new crystal forms as well as in solving problems related to polymorphism and crystallization.

The selection of a suitable solid form is a vital step in drug substance development. Solid forms determine bioavailability, solubility, dissolution rate, stability and manufacturability.

The route of application and the intended daily dose play an important role within solid form selection. For example, the solid-state property requirements depend on whether an oral, parenteral, transdermal or inhalation route is the desired method of administration.

We help you walk the smartest path to the clinic by guiding the selection of optimal crystal forms with a series of preformulation studies, including:

Solubility and dissolution rate in aqueous media and simulated body fluids at various pH values

Increasing drug development costs and greater competition are forcing the pharmaceutical industry to explore the true potential of existing molecules in order to maintain or extend patent protection.

The quest to stretch a molecule’s lifecycle has become at least as important as the discovery and development of new drug candidates.

We leverage solid-state research capabilities to provide insights and techniques to assist with lifecycle management.

Get in touch to see how we can craft your path to the clinic with dedicated capabilities.

Helping you turn your compounds that show promise into GMP-grade drug substances.

We advance your clinical candidates through the pipeline quickly and safely with specialist drug product services.